Mr. and Mrs. Blandings is an American radio situation comedy that was broadcast on NBC from January 21, 1951, to June 17, 1951. Based on the novels Mr. Blandings Builds His Dream House and Blandings Way, written by Eric Hodgins, the series featured Cary Grant in his first regular role on a radio program, and it was the first network radio series sponsored by an airline (TWA).

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